How much bromadiolone is toxic to dogs?

A safe or toxic amount cannot be determined from bait weight alone. Product concentration, amount ingested, body weight, timing, and the exact active ingredient must be confirmed. This tool calculates exposure in mg/kg but intentionally does not assign bromadiolone a safe or low-risk threshold; contact a veterinarian or animal poison-control service immediately.

Are bromadiolone and bromethalin the same?

No. Bromadiolone is a second-generation anticoagulant associated with delayed bleeding. Bromethalin is a neurotoxic rodenticide that can cause neurologic signs and has no specific antidote. Check the product label because the names are easy to confuse.

How quickly can anticoagulant rodenticide signs appear?

Clinical evidence of coagulopathy can be delayed for several days after ingestion. A patient that looks normal still needs prompt veterinarian or animal poison-control assessment.

Clinical decision support

Rodenticide toxicity calculator

Calculate active-ingredient exposure in mg/kg for dogs and cats. This tool does not establish a safe amount, and bromadiolone results require toxicology review.

Reference ranges & assumptions

Editable threshold assumptions for other ingredients (mg/kg active ingredient)

Warfarin — Dog Warfarin — Cat

Bromadiolone: no default toxic threshold is assigned. The calculator reports exposure arithmetic only because an exact, current dog/cat threshold was not verified for this candidate. Do not interpret the result as safe or below treatment level.

Difenacoum — Dog Difenacoum — Cat

Brodifacoum — Dog Brodifacoum — Cat

Bromethalin — Dog Bromethalin — Cat

Cholecalciferol — monitoring threshold Cholecalciferol — high-risk threshold

Vitamin K1 dosing

Vitamin K1 q12h dose (mg/kg) Vitamin K1 q24h alternative (mg/kg)

Remaining editable LD50 values are assumptions and vary by source. Bromethalin cats use the lower Merck/MSD sensitivity range. Cholecalciferol uses clinical monitoring thresholds because toxic changes occur far below LD50. Vitamin K1 should be given with a fatty meal for absorption.

Active ingredient dose

— mg/kg

Enter values

Enter weight, bait concentration, and amount to calculate.

Risk level —

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Expected onset —

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Specific antidote —

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Monitoring plan —

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Clinical next steps

Recent exposure may be eligible for veterinarian-directed decontamination. Do not induce vomiting or administer charcoal unless a veterinarian or animal poison-control service directs it.
Anticoagulants: Vitamin K1 (phytonadione) is the antidote when indicated. Merck/MSD lists 2.5 mg/kg PO q12h or 5 mg/kg PO q24h for 28 days, with confirmed warfarin sometimes shorter. Recheck PT 2–3 days after stopping.
Bromethalin: No specific antidote exists. Treatment is supportive and veterinarian-directed. Current MSD guidance describes corticosteroids as controversial and unlikely to help bromethalin-associated cerebral edema.
Cholecalciferol: Aggressive IV fluids (0.9% NaCl) to promote calciuresis. Monitor ionized calcium, phosphorus, BUN, creatinine. Furosemide and prednisone may help. Pamidronate for severe hypercalcemia.
For all exposures: baseline CBC, chemistry panel, and urinalysis. Monitor as indicated by toxicant type.

Safety checks

This tool supports calculation and education only.
It does not diagnose, prescribe, or replace current clinical references.
Verify patient-specific decisions with current toxicology references, hospital protocols, and veterinarian judgment.
Bait concentrations vary by product. Always verify the specific product label when possible.
Second-generation anticoagulants (bromadiolone, difenacoum, brodifacoum) have longer half-lives and require longer vitamin K1 therapy.

Basis and limits

Calculation basis: Active ingredient (mg) = bait amount (g) × concentration (% as decimal) × 1000. Or if ppm: mg = g × (ppm / 1,000,000) × 1000. Dose (mg/kg) = total mg / body weight (kg).
Assumed thresholds: editable non-bromadiolone anticoagulant and bromethalin defaults compare exposure to one-tenth of LD50, a conservative treatment-threshold estimate. Bromadiolone is exposure arithmetic only and never receives a low-risk label. Cholecalciferol uses lower clinical monitoring thresholds because toxic changes may occur far below LD50. Confirm all assumptions against current ingredient- and species-specific references.
Anticoagulant monitoring: PT is the most sensitive coagulation test for anticoagulant rodenticide toxicity. Prolongation precedes clinical bleeding.
Scope: this tool estimates exposure. It does not replace toxicology consultation or clinical judgment.

Formula audit trail

1. Convert bait amount to grams if entered in ounces (oz × 28.35).

2. Convert concentration to % if entered in ppm (ppm ÷ 10,000).

3. Active ingredient (mg) = bait (g) × (% / 100) × 1000.

4. Dose (mg/kg) = active ingredient (mg) / body weight (kg).

5. Interpret carefully. Compare only when a verified ingredient-specific threshold is available. Bromadiolone reports exposure arithmetic without a threshold or safe-dose classification.

Calculation steps will appear here for verification.

Related tools

Last source review: August 11, 2026

Sources: MSD Veterinary Manual: Anticoagulant Rodenticide Poisoning; MSD Veterinary Manual: Bromethalin Poisoning; National Pesticide Information Center: Bromadiolone

Bromadiolone and bromethalin are not the same poison

How much bromadiolone is toxic to a dog?

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